AntibodiesNeuroMab

Anti-KCNC1 Antibody-Oligo Conjugate

SKU: aoc21

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Assay

Immunofluorescence Oligossee protocol

IF1 Oligo Details

5'
AATATGGAATTCGTCCGAGCCCGTCAAG
3'

View Paper

Accessory oligo is complementary to only the ab-conjugated oligo

Anti-KCNC1 Antibody-IF1

Antibody Target

Target
KCNC1
UniProt Number
P48547
Target Description
Voltage-gated potassium channel that opens in response to the voltage difference across the membrane and through which potassium ions pass in accordance with their electrochemical gradient (PubMed:25401298, PubMed:35840580). The mechanism is time-dependent and inactivation is slow (By similarity). Plays an important role in the rapid repolarization of fast-firing brain neurons (By similarity). Can form functional homotetrameric channels and heterotetrameric channels that contain variable proportions of KCNC2, and possibly other family members as well (By similarity). Contributes to fire sustained trains of very brief action potentials at high frequency in pallidal neurons (By similarity)..
Molecular Weight
110 kDa
Synonyms
Potassium voltage-gated channel subfamily C member 1 (NGK2) (RAW2) (Voltage-gated potassium channel subunit Kv3.1) (Voltage-gated potassium channel subunit Kv4)

Antibody Characteristics

Clonality
Monoclonal
Application
WBIHCICCIP
Specificity
No cross-reactivity reported
Clone
N16B/8
Isotype
IgG1
Form
Liquid
Immunogen
Fusion protein amino acids 437-585 (cytoplasmic C-terminus) of rat Kv3.1b (accession number P25122) produced recombinantly in E. Coli
Immunogen Species
Rat
Host Species
Mouse
Species Reactivity
HamsterHumanMonkey (Non-Human Primate)MouseRat
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